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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">eifc</journal-id><journal-title-group><journal-title xml:lang="ru">Эпизоотология Иммунобиология Фармакология Санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Epizootology Immunobiology Pharmacology Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2224-168X</issn><publisher><publisher-name>Институт экспериментальной ветеринарии им. С.Н. Вышелесского</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">eifc-36</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИММУНОБИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>IMMUNOBIOLOGY</subject></subj-group></article-categories><title-group><article-title>Адаптация штамма реовируса птиц «S1133» к перевиваемой культуре клеток Vero и разработка на его основе технологии изготовления высокоиммуногенных убитых вакцин</article-title><trans-title-group xml:lang="en"><trans-title>Adaptation of the strain of reovirus birds «S1133» to the transplantable cell culture Vero and development on its basis of manufacturing technology highly immunogenous killed vaccines</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Радюш</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Radyush</surname><given-names>I. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>06</month><year>2019</year></pub-date><volume>0</volume><issue>1</issue><fpage>25</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Радюш И.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Радюш И.С.</copyright-holder><copyright-holder xml:lang="en">Radyush I.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://eifc.belal.by/jour/article/view/36">https://eifc.belal.by/jour/article/view/36</self-uri><abstract><p>В статье представлены данные по адаптации штамма реовируса птиц «S1133» к перевиваемой культуре клеток Vero и разработке отечественной инактивированной вакцины для профилактики реовирусной инфекции птиц. Установлено, что препарат стимулирует образование антител к реовирусу птиц в защитных титрах в организме иммунизированных кур, не уступая по своей профилактической эффективности зарубежным аналогам.</p></abstract><trans-abstract xml:lang="en"><p>The article presents data on the adaptation of the avian reovirus strain S1133 to continuous Vero cell culture and the development of the domestic inactivated vaccine for the prevention the reovirus infection of avian. It is established that the drug stimulates the formation of antibodies to reovirus in protective titers in the body of immunized chickens, not inferior in its preventive effectiveness to foreign analogues.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
