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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">eifc</journal-id><journal-title-group><journal-title xml:lang="ru">Эпизоотология Иммунобиология Фармакология Санитария</journal-title><trans-title-group xml:lang="en"><trans-title>Epizootology Immunobiology Pharmacology Sanitation</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2224-168X</issn><publisher><publisher-name>Институт экспериментальной ветеринарии им. С.Н. Вышелесского</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">eifc-56</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФАРМАКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>FARMACOLOGY</subject></subj-group></article-categories><title-group><article-title>Эффективность применения комплексного иммуностимулирующего препарата «Нуклеозан» на основе нуклеината натрия и липополисахаридов бактерий</article-title><trans-title-group xml:lang="en"><trans-title>Efficiency of application of the complex immunity of the «Nucleosan» multipreparating basis on the basis of sodium nucleate and bacteria lipopolysaccharides</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисовец</surname><given-names>Д. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisovets</surname><given-names>D. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зуйкевич</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zuykevich</surname><given-names>T. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Красочко</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Krasochko</surname><given-names>P. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozov</surname><given-names>A. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Толяронок</surname><given-names>Г. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Tolyaronok</surname><given-names>G. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ястребов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Yastrebov</surname><given-names>A. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>УО «Витебская ордена «Знак Почета» государственная академия ветеринарной медицины»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>12</month><year>2019</year></pub-date><volume>0</volume><issue>2</issue><fpage>58</fpage><lpage>62</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Борисовец Д.С., Зуйкевич Т.А., Красочко П.А., Морозов А.М., Толяронок Г.Е., Ястребов А.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Борисовец Д.С., Зуйкевич Т.А., Красочко П.А., Морозов А.М., Толяронок Г.Е., Ястребов А.С.</copyright-holder><copyright-holder xml:lang="en">Borisovets D.S., Zuykevich T.A., Krasochko P.A., Morozov A.M., Tolyaronok G.E., Yastrebov A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://eifc.belal.by/jour/article/view/56">https://eifc.belal.by/jour/article/view/56</self-uri><abstract><p>В статье изложены результаты разработки и испытаний комплексного иммуностимулирующего препарата «Нуклеозан». Основными компонентами препарата являются нуклеинат натрия и липополисахариды. Для пролонгации препарата использован поливинилпирролидон. Оптимальная доза изготовленного препарата «Нуклеозан» для молодняка крупного рогатого скота составляет 2,0 см3. Установлено также, что препарат «Нуклеозан» при совместном использовании с вакциной стимулирует иммуногенез у животных.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the results of the development and testing of the complex immunostimulating drug «Nucleosan». The main components of the preparation are: sodium nucleinate, lipopolysaccharides. To prolong the drug used polyvinylpyrrolidone. The optimal dose of the manufactured drug «Nucleosan» for young cattle is 2,0 cm3. It was also found that the drug «Nucleosan» when used together with the vaccine stimulates immunogenesis in animals.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
