eifcЭпизоотология Иммунобиология Фармакология СанитарияEpizootology Immunobiology Pharmacology Sanitation2224-168XИнститут экспериментальной ветеринарии им. С.Н. Вышелесского10.47612/2224-168X-2021-2-7-11eifc-99Research ArticleЭПИЗООТОЛОГИЯEPIZOOTOLOGYВыявление и генетическое типирование (по региону 5'-UTR) изолятов вируса вирусной диареи КРС, циркулирующих на территории Республики БеларусьDetection and genetic typing (by region 5'-UTR) of isolates of bovine viral diarrhea virus circulating in the territory of the Republic of BelarusДубаневичО. В.DubanevichO. V.

старший научный сотрудник

г. Минск

ТяпшаЮ. И.TyapshaYu. I.

кандидат ветеринарных наук, доцент

г. Минск

РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»Belarus20210602202202711Copyright © Дубаневич О.В., Тяпша Ю.И., 20222022Дубаневич О.В., Тяпша Ю.И.Dubanevich O.V., Tyapsha Y.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://eifc.belal.by/jour/article/view/99

Вирус вирусной диареи крупного рогатого скота (BVDV) вызывает значительные экономические потери. BVDV имеет высокое геномное разнообразие: два генотипа вируса вирусной диареи, где двадцать один субгенотип у BVDV-1 и четыре субгенотипа у BVDV-2. Вакцины – важный инструмент для уменьшения экономических потерь, вызванных этим вирусом. Однако штаммы вакцины должны соответствовать антигенному профилю вирусов, циркулирующих в регионе, где применяется вакцина. Филогенетическое исследование 13 изолятов вируса, циркулирующих на территории Республики Беларусь, показало, что генетический профиль BVDV состоял в превалирующем большинстве из субтипов BVDV-1f (76,9 %) и BVDV-1a (15,0 %) генотипа 1, в одном хозяйстве обнаружен субтип BVDV-2a генотипа 2.

Bovine viral diarrhea virus (BVDV) causes serious economic losses. BVDV has high genomic diversity: two viral diarrhea virus genotypes, with twenty-one subgenotypes for BVDV-1 and four subgenotypes for BVDV-2. Vaccines are important tools for reducing the economic losses caused by this virus. However, the strains of the vaccine match the antigenic profile of the viruses circulating in the area where the vaccine is. A phylogenetic study of 13 virus isolates circulating in the territory of the Republic of Belarus showed that the genetic profile of BVDV consisted in the overwhelming majority of subtypes BVDV-1f (76.9 %) and BVDV-1a (15.0 %), genotype 1, in one farm the subtype was found BVDV-2a genotype 2.

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The authors declare that there are no conflicts of interest present.