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Obtaining transovarian immunoglobulins when creating new veterinary biological products

https://doi.org/10.47612/2224-168X-2021-2-31-39

Abstract

The methods of obtaining of transovarial immunoglobulins for the development of veterinary biological preparation of a new generation are shown in the article. In the process of the research, the most effective method of isolating of transovarial immunoglobulins was determined - the method using organic solvents, and also the most optimal way to purify them by precipitation using PEG-6000, which allows to obtain the maximum result at relatively low cost. The results of the study of structural and functional features of the obtained yolk immunoglobulins of laying hens IgY in a comparative aspect are presented

About the Authors

D. S. Borisovets
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Belarus


T. A. Zuykevich
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Belarus


A. A. Zgirovskaya
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Belarus


P. A. Krasochko
УО «Витебская ордена «Знак Почета» государственная академия ветеринарной медицины»
Belarus


A. E. Osipenko
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Belarus


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For citations:


Borisovets D.S., Zuykevich T.A., Zgirovskaya A.A., Krasochko P.A., Osipenko A.E. Obtaining transovarian immunoglobulins when creating new veterinary biological products. Epizootology Immunobiology Pharmacology Sanitation. 2021;(2):31-39. (In Russ.) https://doi.org/10.47612/2224-168X-2021-2-31-39

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ISSN 2224-168X (Print)