Features of immunobiological manifestation of Blastocystosis in calves
Abstract
Blastocystosis, caused by the protest Blastocystis spp., is a widespread but understudied invasion in farm animals, whose pathogenic role remains controversial.
Microscopic examination of 288 fecal samples from calves up to 30 days old confirmed the invasion in 72 samples (25 % of cases). A comparative immunological analysis of blood from infected and pathogen-free calves revealed statistically significant changes. In diseased calves, a significant decrease in the relative count of total Tlymphocytes (CD3+) by 18,86 % and T-helper cells (CD4+) by 1,81 % was established, indicating the immunosuppressive effect of the pathogen. Simultaneously, lymphopenia (a decrease of 23,04 %) and a significant increase in the level of band neutrophils (by 1,62 times) were noted, indicating the development of a pronounced inflammatory process.
The data obtained indicate that blastocystosis in calves is accompanied by a complex violation of the immune response, characterized by an imbalance in the cellular link of immunity and chronic inflammation. This must be taken into account when developing treatment and preventive measures.
About the Authors
N. Yu. Shchemeleva
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Belarus
Belarus
V. P. Vasilkova
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Belarus
Belarus
I. A. Romanchik
Белорусский государственный университет
Belarus
Belarus
References
1. Максимова, М. С. Взаимосвязь между интенсивностью выделения Blastocystis sp. и проявлениями дисфункции желудочно-кишечного тракта / М. С. Максимова, Т. В. Продеус // Инфекционные болезни: новости, мнения, обучение. – 2018. – Т. 7. – № 4 (27). – С. 52–57.
2. Об ассоциации Blastocystis species и микробиоты кишечника при различных состояниях макроорганизма / М. С. Максимова, Т. В. Продеус, Л. В. Федянина, О. В. Грицюк // Медицинская паразитология и паразитарные болезни. – 2015. – № 4. – С. 55–58.
3. Продеус, Т. В. Морфологическая идентификация бластоцист / Т. В. Продеус, Л. В. Федянина, А. А. Фролова // Медицинская паразитология и паразитарные болезни. – 2014. – № 1. – С. 9–13.
4. Blastocystis tropism in the pig intestine / R. Fayer, T. Elasser, R. Gould [ et al.] // Parasitol Res. – 2014. – № 113 (4) – P. 1465–72.
5. Elwakil, H. S. Pathogenic potential of Blastocystis in laboratory mice / H. S. Elwakil, I. H. Hewedi // Parasitol. Res. – 2010. – № 107 (3) – P. 685–9.
6. Tan, K. S. W. New insights on classification, identification, and clinical relevance of Blastocystis spp. / K. S. W. Tan // Clin Microbiol Rev. – 2008. – Vol. 21, n 4. – P. 639–665.
7. Zierdt, C. H. Studies of Blastocystis / C. H. Zierdt // J. Protozool. – 1973. – Vol. 20. – P. 114–121.
8. Zierdt, C. H. Taxonomic status of Blastocystis: reply / C. H. Zierdt // Parasitol. Today. – 1993. – Vol. 9. – P. 18–19.
Review
For citations:
Shchemeleva N.Yu., Vasilkova V.P., Romanchik I.A. Features of immunobiological manifestation of Blastocystosis in calves. Epizootology Immunobiology Pharmacology Sanitation. 2025;(2):8-13. (In Russ.)
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