Adaptation of the strain of reovirus birds «S1133» to the transplantable cell culture Vero and development on its basis of manufacturing technology highly immunogenous killed vaccines

Abstract

The article presents data on the adaptation of the avian reovirus strain S1133 to continuous Vero cell culture and the development of the domestic inactivated vaccine for the prevention the reovirus infection of avian. It is established that the drug stimulates the formation of antibodies to reovirus in protective titers in the body of immunized chickens, not inferior in its preventive effectiveness to foreign analogues.