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Toxicological characterization of new multicomponent antimastitis preparation «Mastin» for the treatment of mastitis in cows

Abstract

Data on the toxicological characteristics of the new complex preparation «Mastin» for the treatment of mastitis in cows are presented in the article, data on determination of its toxicity are given, еxperience on determination of chronic toxicity of preparation on laboratory animals is described. It was found that LD50 of the antimastitis drug at the oral dose for white mice was 37 250,55 mg / kg of body weight. The drug is a low-risk substance (IV class) with LD50 more than 5000 mg/kg.

About the Authors

E. A. Stepanova
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Russian Federation


I. I. Kuzminski
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Russian Federation


A. V. Lilenko
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Russian Federation


A. A. Bogush
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Russian Federation


A. F. Trofimov
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Russian Federation


Review

For citations:


Stepanova E.A., Kuzminski I.I., Lilenko A.V., Bogush A.A., Trofimov A.F. Toxicological characterization of new multicomponent antimastitis preparation «Mastin» for the treatment of mastitis in cows. Epizootology Immunobiology Pharmacology Sanitation. 2018;(1):59-62. (In Russ.)

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ISSN 2224-168X (Print)