Mycobacteria are found in cultural liquid of fetal lamb kidney cells infected with bovine leukemia virus
Abstract
In all investigated 13 lots of antigens for diagnostics of bovine leukemia (concentrated cultural liquid of fetal lamb kidney cells infected bovine leukemia virus FLK-BLV) are found typical and cell wall deficient mycobacteria (CWD) and isolated CWD forms of mycobacteria including the lots of FLK-BLV filtrated from 0,22 Millex®GP. CWD isolates after inoculation to guinea pigs are stimulated of synthesis of antibody reacting in AGID with FLK-BLV. The same antibody appeared after inoculation to guinea pigs of homogenates of internals guinea pigs infected by isolates from FLK-BLV. It is assumed that the BLV can be virus-like form of mycobacteria tuberculosis. The possible role in cancer genesis of latent tuberculosis infection BCG and tuberculin is considered.
About the Authors
A. P. Lysenko
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Russian Federation
E. L. Vlasenko
Винницкий национальный аграрный университет
Russian Federation
E. L. Krasnikova
РУП «Институт экспериментальной ветеринарии им. С.Н. Вышелесского»
Russian Federation
L. .. Broxmeyer
N. Y. Institute of Medical Research in Bayside
Russian Federation
For citations:
Lysenko A.P.,
Vlasenko E.L.,
Krasnikova E.L.,
Broxmeyer L...
Mycobacteria are found in cultural liquid of fetal lamb kidney cells infected with bovine leukemia virus. Epizootology Immunobiology Pharmacology Sanitation. 2018;(1):7-17.
(In Russ.)
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