The article presents the results of a partial sequence isolated in the Republic of Belarus of isolates of the virus of reproductive and respiratory syndrome. Sequence analysis indicates significant polymorphism of isolates in the most conservative reading frames (OPC6-7). Isolated isolates belong to the European type, subtype 3.

This article shows that the response of the mammalians organism to mixtinvasion depends on the order of penetration of the parasite into the host organism and the dose of infection. With a combination of nematodes and bacteria, the nematodes has been a leading role in the first stage, but subsequently, bacteria begin to exert a depressing effect on helminthes and the role of bacteria becomes a priority. In the combination of nematodes and eimeria during primary infection, nematodes do not significantly affect the survival of eimeria, however, the effect of eimeria on nematodes can be assessed as antagonistic. In this case, the response of the host to the second invasion changes under the influence of the first. It has been established that between helminthes and microflora of the gastrointestinal tract of mammals there is a pronounced antagonism.

From the cultures cells of myeloblasts of the human patient with acute myeloid leukemia (Kasumi-1) and T-lymphocytes the patient with T-lymphoblastic leukemia (Jurkat) including from 0.22 µm filtrates of cells lysates there are isolated mycobacteria of tuberculosis (MBT) with deficient cell wall (cell wall deficient - CWD) with the same of antigens composition. Isolates had a number of unique properties. After destruction by ultrasound and filtration through Amicon Ultracel® 100 K and Millex ® GP 0.22 µm their filtrates gave growth of CWD MBT having the same antigenic composition, including starting isolates. The main role in the isolation of CWD MBT was the incubation of the test material in the growth stimulants, sowing on a special nutrient medium and «blind» passages.

The article presents data on the biochemical properties of the museum strains of Salmonella dublin, Salmonella cholerae suis, Salmonella typhimurium, distinguishing features of the fermentation of individual substances are established. Serovariate accessories of the museum strains were confirmed in the polymerase chain reaction using the developed by RUE «Institute of Experimental Veterinary Medicine named after S.N. Vysheleskogo» test systems for the detection of the genomes of Salmonella dublin, Salmonella cholerae suis, Salmonella typhimurium.

The results of phagocytic activity of leukocytes after administration of samples of the preparation based on zinc nanoparticles are described. The immunostimulating effect of zinc nanoparticle-based drug samples during vaccination against infectious rhinotracheitis and viral diarrhea in animals is evaluated. Data on the main blood parameters before use and 7 and 14 days after its use are presented.

This article presents the research data of detection strain-producer of Escherichia coli heat-labile enterotoxin and determining of its ability to toxin formation in industrial cultivation. It was established, the concentration of heatlabile enterotoxin in the culture medium is 23 ng/ml

The toxicological parameters of a complex preparation intended for the treatment and prevention of associative helminthiasis in cattle have been studied - this is an acute and chronic toxicity irritating and sensitizing properties of the drug on laboratory animals

The article presents the results of preclinical research of the study of embryotoxic and teratogenic, skin-resorptive effects of an experimental sample of a new veterinary drug for laboratory animals - white rats. Based on the research the results obtained, that the pharmaceutical composition has not embryotoxic and teratogenic effects on the embryos and newborns of laboratory animals, and also does not have a skin-resorptive effect for skin.

The article describes material on the morphology of the thyroid gland in rabbits in postnatal ontogenesis and under the influence of the drug «Chromarcin». The morphological and functional features of the structural thyroid gland and the positive dynamics of the pattern of increase in the height of the thyroid epithelium under the influence of the drug are established.

The method of obtaining zinc nanoparticles is described. The results of studies of zinc nanoparticles using atomic force microscopy are presented. The results of testing the drug for acute toxicity are presented.

The complex effect of mineral-based sanitary products has an impact on all stages of development of flies, leading to a marked decrease in the activity of their brood, which allows them to be used in livestock facilities to obtain biologically pure products